Enzo Agostinelli Selected Research

Amines

10/2016	Ternary Hybrid γ-Fe2 O3 /Cr(VI) /Amine Oxidase Nanostructure for Electrochemical Sensing: Application for Polyamine Detection in Tumor Tissue.
10/2016	Milestones and recent discoveries on cell death mediated by mitochondria and their interactions with biologically active amines.
1/2015	Nanoparticle strategies for cancer therapeutics: Nucleic acids, polyamines, bovine serum amine oxidase and iron oxide nanoparticles (Review).
9/2014	The combined treatment with chloroquine and the enzymatic oxidation products of spermine overcomes multidrug resistance of melanoma M14 ADR2 cells: a new therapeutic approach.
9/2013	Hyaluronic acid nanohydrogels as a useful tool for BSAO immobilization in the treatment of melanoma cancer cells.
9/2013	Reactive oxygen species spermine metabolites generated from amine oxidases and radiation represent a therapeutic gain in cancer treatments.
9/2009	Cytotoxicity of spermine oxidation products to multidrug resistant melanoma M14 ADR2 cells: sensitization by the MDL 72527 lysosomotropic compound.
1/2008	Mechanism of cell death induced by spermine and amine oxidase in mouse melanoma cells.
10/2006	Sensitization of human colon adenocarcinoma cells (LoVo) to reactive oxygen species by a lysosomotropic compound.
10/2006	Toxicity of enzymatic oxidation products of spermine to human melanoma cells (M14): sensitization by heat and MDL 72527.

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Enzo Agostinelli Research Topics

Disease

37	Neoplasms (Cancer) 06/2022 - 05/2002
6	Melanoma (Melanoma, Malignant) 09/2014 - 06/2005
4	Medulloblastoma 11/2020 - 10/2015
4	Colonic Neoplasms (Colon Cancer) 06/2019 - 05/2002
3	Neuroblastoma 01/2021 - 11/2019
3	Necrosis 10/2016 - 06/2005
2	Breast Neoplasms (Breast Cancer) 03/2014 - 05/2013
2	Hyperthermia 03/2014 - 06/2006
2	Prostatic Neoplasms (Prostate Cancer) 03/2014 - 01/2014
2	Hepatocellular Carcinoma (Hepatoma) 05/2012 - 02/2012
1	Squamous Cell Carcinoma of Head and Neck 05/2022
1	Head and Neck Neoplasms (Head and Neck Cancer) 01/2022
1	Proliferative Vitreoretinopathy 07/2021
1	Myotonic Dystrophy (Dystrophia Myotonica) 01/2021
1	Epilepsy (Aura) 01/2020
1	Mental Disorders (Mental Disorder) 01/2020
1	Brain Diseases (Brain Disorder) 01/2020
1	Autoimmune Diseases (Autoimmune Disease) 05/2019
1	Pathologic Processes 09/2018
1	Pituitary Neoplasms (Pituitary Adenoma) 10/2017
1	Retinal Vein Occlusion 10/2016
1	Macular Edema 10/2016
1	Cholangiocarcinoma 01/2015
1	Obesity 01/2014

Drug/Important Bio-Agent (IBA)

18	PolyaminesIBA 06/2022 - 06/2005
14	SpermineIBA 01/2021 - 05/2002
13	Oxidoreductases (Dehydrogenase)IBA 10/2016 - 06/2005
12	AminesIBA 10/2016 - 06/2005
8	AldehydesIBA 09/2014 - 05/2002
7	EnzymesIBA 01/2015 - 06/2005
6	Pharmaceutical PreparationsIBA 06/2022 - 05/2002
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2017 - 08/2016
4	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2016 - 10/2006
4	Proteins (Proteins, Gene)FDA Link 01/2015 - 09/2007
4	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 09/2013 - 10/2006
3	Polyamine OxidaseIBA 11/2019 - 03/2014
3	SpermidineIBA 06/2019 - 01/2008
2	Antineoplastic Agents (Antineoplastics)IBA 06/2022 - 05/2002
2	AntioxidantsIBA 01/2022 - 09/2018
2	Caspase 3 (Caspase-3)IBA 01/2021 - 01/2008
2	Nucleic AcidsIBA 01/2021 - 01/2015
2	Therapeutic UsesIBA 11/2020 - 11/2019
2	LigandsIBA 01/2020 - 08/2016
2	Transcription Factors (Transcription Factor)IBA 11/2019 - 01/2019
2	AndrogensIBA 03/2014 - 01/2014
2	PutrescineIBA 01/2014 - 01/2008
2	Biomarkers (Surrogate Marker)IBA 05/2013 - 05/2012
2	MDL 72527IBA 09/2009 - 10/2006
1	bispidineIBA 06/2022
1	Culture MediaIBA 06/2022
1	1,2-diazabicyclo(3.3.1)nonaneIBA 06/2022
1	Nerve Growth Factor Receptor (Nerve Growth Factor Receptor, Low Affinity)IBA 05/2022
1	PolyphenolsIBA 01/2022
1	Alkylating AgentsIBA 01/2022
1	CurcuminIBA 07/2021
1	Carrier Proteins (Binding Protein)IBA 01/2021
1	RNA (Ribonucleic Acid)IBA 01/2021
1	Hypoglycemic Agents (Hypoglycemics)IBA 11/2020
1	Co-Repressor ProteinsIBA 11/2020
1	Phenformin (Fenformin)IBA 11/2020
1	BiguanidesIBA 11/2020
1	Cysteine (L-Cysteine)FDA Link 02/2020
1	Ionotropic Glutamate ReceptorsIBA 01/2020
1	Ion Channels (Ion Channel)IBA 01/2020
1	HhAntag691IBA 01/2019
1	MitogensIBA 01/2019
1	NocodazoleIBA 01/2019
1	Phosphotransferases (Kinase)IBA 01/2019
1	5,5',6,6'- tetrachloro- 1,1',3,3'- tetraethylbenzimidazolocarbocyanineIBA 09/2018
1	Fluorescent Dyes (Fluorescent Probes)IBA 09/2018
1	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 10/2017
1	Epidermal Growth Factor (EGF)IBA 10/2017
1	Ciliary Neurotrophic Factor (CNTF)IBA 10/2017
1	Nerve Growth Factor (NGF)IBA 10/2017
1	Nerve Growth Factors (Neurotrophins)IBA 10/2017
1	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 10/2017
1	Biological ProductsIBA 10/2017
1	Growth InhibitorsIBA 10/2017
1	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 06/2017
1	Angiogenesis InhibitorsIBA 06/2017
1	Dexamethasone (Maxidex)FDA LinkGeneric 10/2016
1	chromium hexavalent ionIBA 10/2016
1	Oxygen (Dioxygen)IBA 01/2015
1	Chloroquine (Aralen)FDA LinkGeneric 09/2014
1	DNA (Deoxyribonucleic Acid)IBA 03/2014
1	ornithine decarboxylase antizymeIBA 03/2014
1	OligonucleotidesIBA 03/2014
1	Ornithine Decarboxylase (Decarboxylase, Ornithine)IBA 03/2014
1	A-Form DNA (A-DNA)IBA 03/2014
1	Pyruvate KinaseIBA 01/2014
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2014
1	Anti-Obesity Agents (Antiobesity Drugs)IBA 01/2014
1	RoscovitineIBA 01/2014
1	Hormones (Hormone)IBA 01/2014
1	Androgen Receptors (Androgen Receptor)IBA 01/2014

Therapy/Procedure

17	Therapeutics 04/2022 - 10/2006
3	Drug Therapy (Chemotherapy) 10/2006 - 05/2002
1	Phacoemulsification 10/2016
1	Intravitreal Injections 10/2016
1	Intraocular Lens Implantation 10/2016